Research Ideas ?
1. Do obese people tolerate sub-massive PE better than non obese ?
2. Do steroids help in subsequent admissions with respiratory failure when they had COVID related hospitalization in previous admission ?
3. Passive leg raise test in acute PE - can this be used to figure out if patient needs IV fluids or lasix ? Similarly can you use this in complicated RHF patients - e.g. RHF and sepsis to give either fluid or lasix.
4. Are the Hounsefield unit for clot and blood different on CT scan ? If so, can you differentiate intravascular clots without need for a contrast. Are there subtle changes in vascular diameter in acute PE ? Do you think we can train neural network/machine learning to diagnose acute PE without contrast ?
5. Does placing sandbag on chest have similar results of improving oxygenation in hypoxemic ARDS patients who cannot be proned ?
6. Can you train AI to lip read your intubated patient ? think about how easy the communication can be.
7. Does changing position (sitting, lateral position, prone) affects VQ or oxygenation or hemodynamics in acute PE ? I hypothesize it should, if PE is asymetrical.
8. lactate in sepsis can be produced from many other pathways apart from 'low perfusion'. In early sepsis, low perfusion is not common and most of lactate comes from diversion of glycolysis away from krebs cycle. However, low perfusion would be more serious form of sepsis and should be differentiated. So if lactate is positive, it should be important to know whether its just from diversion away from Kreb cycle or from 'hypoperfusion'. Patients with hypoperfusion should have worse sepsis, even if their lactate is similar. Can you use changes in VCO2 (on ventilator) or PvCO2 to figure out whether there is low perfusion and anerobic metabolism.
9. Make a chat GPT which can interview people. Since it is also a great fact checker, the interview can really be useful and bias free. most of the interviewer are mostly ignorant of true facts and deep understanding of the topic they are interviewing on and accept any answers thrown at them or their biases prevent them from getting a good answers.
10. Does altitude increases risk for developing clots and pulmonary embolism?
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An Empirical Study of Speech Processing in the Brain by Analyzing the Temporal Syllable Structure in Speech-input Induced EEG