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PUBLICATIONS

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

- Claude Bernard -

Journal Publications

  1. “Outcomes of Covid 19 Patients - Are Hispanics at greater risk?” Nanchal R, Patel D, Guddati AK, Sakhuja A, Meersman M, Dalton D, Kumar G. Journal of Medical Virology. 2021 Oct 11. PMID: 34633096

  2. “Do High Dose Corticosteroids Improve Outcomes in Hospitalized COVID-19 Patients?”  Gagan Kumar, Dhaval Patel, Martin Hererra, David Jefferies, Ankit Sakhuja, Mark Meersman, Drew Dalton, Rahul Nanchal, Achuta Kumar Guddati. Journal of Medical Virology. 2021 Sep 24. PMID: 34559436

  3. “Incidence of Venous Thromboembolism and Effect of Anticoagulant Dosing in Hospitalized COVID-19 Patients”. Gagan Kumar, Dhaval Patel, Tariq Odeh, Erine Rojas, Ankit Sakhuja, Mark Meersman, Drew Dalton, Rahul Nanchal, Achuta Kumar Guddati. Journal of Hematology. 2021;10(4):162-170.

  4. “Does ABO Blood Groups Affect Outcomes in Hospitalized COVID-19 Patients?” G Kumar, R Nanchal, M Hererra, A Sakhuja, D Patel, M Meersman, D Dalton, AK Guddati.  Journal of Hematology 2021 Jun;10(3):98-105. PMID: 34267846.

  5. “Predictors and Outcomes of Healthcare Associated Infections in COVID-19 Patients”. Gagan Kumar, Alex Adams, Martin Herrera, Erine Raybon-Rojas, Vartika Singh, Ankit Sakhuja, Mark Meersman, Drew Dalton,Shravan Kethireddy, Rahul Nanchal, Achuta Kumar Guddati. International Journal of Infectious Diseases. 2021 Mar; 104:287-292. PMID: 33207271.

  6. “Outcomes of Adult Critically Ill Patients with Hemophagocytic Lymphohistiocytosis in United States – Analysis from an Administrative Database from 2007 to 2015”. Gagan Kumar, Martin Hererra, Dhaval Patel, Rahul Nanchal, Achuta Kumar Guddati. American Journal of Blood Research. 2020 Dec 15;10(6):330-338. PMID: 33489441.

  7. “Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary and Renal Considerations: Executive Summary”. Nanchal R, Subramanian R, Karvellas CJ, Hollenberg SM, Peppard WJ, Singbartl K, Truwit J, Al-Khafaji AH, Killian AJ, Alquraini M, Alshammari K, Alshamsi F, Belley-Cote E, Cartin-Ceba R, Dionne JC, Galusca DM, Huang DT, Hyzy RC, Junek M, Kandiah P, Kumar G, Morgan RL, Morris PE, Olson JC, Sieracki R, Steadman R, Taylor B, Alhazzani W. Critical Care Medicine. 2020 Mar;48(3):415-419. PMID: 32058375

  8. “Association of methacholine challenge test with diagnosis of chronic lung allograft dysfunction in lung transplant patients”. Siddiqui AS, Kumar G, Majumdar T, Graviss EA, Nguyen DT, Goodarzi A, Kaleekal T. Clinical Transplantation. 2018 Oct;32(10): e13397. PMID: 30192029

  9. “Analysis of nationwide trends and outcomes of percutaneous endoscopic gastrostomy (PEG) tube placement in hospitalized cancer patients over a 13-year period”. Guddati GA, Kumar G, Shapira L.  Journal of Investigative Medicine. 2018, Jan; 66(1): e1-e2. PMID: 28860116

  10. "Controlled Trial to Improve Resident Sign-Out in a Medical Intensive Care Unit". Nanchal R, Aebly B, Graves G, Truwit J, Kumar G, Taneja A, Dagar G, Graf J, Hubertz E, Ramalingam V, Fletcher KE. BMJ Quality & Safety. 2017. PMID: 28784841

  11. “Cardiac Implantable Electronic Device Infections: Who is at Greatest Risk?” Joy PS, Kumar G, Poole JE, London B, Olshansky B. Heart Rhythm. 2017 Mar 15. S1547-5271(17)30312-0. PMID: 28315744

  12. “Syncope: Outcomes and Conditions Associated with Hospitalization.” Joy PS, Kumar G, Olshansky B. American Journal of Medicine. 2017 Jun;130(6):699-706 PMID: 28147231

  13. “Early intervention results in lower mortality in cancer patients hospitalized for metastatic spinal cord compression". Achuta K Guddati, Gagan Kumar, Luliana Shapira. Journal of Investigative Medicine. 2017 Apr;65(4):787-793. PMID: 28138012

  14. “Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes”. Gupta S, Sakhuja A, Kumar G, McGrath E, Nanchal RS, Kashani KB. CHEST. 2016 Dec;150(6):1251-1259. PMID: 27615024

  15. “Hepatic Encephalopathy-the Old and the New”. Kandiah PA, Kumar G. Critical Care Clinics. 2016 Jul; 32(3):311-2. PMID: 27339673

  16. “Trends and Outcomes of Severe Sepsis in Patients on Maintenance Dialysis”.  Sakhuja A, Nanchal RS, Gupta S, Amer H, Kumar G, Albright RC, Kashani KB. American Journal of Nephrology. 2016; 43(2):97-103.  PMID: 26959243

  17. “Risk Factors and Outcomes of Gastrointestinal Bleeding in Left Ventricular Assist Device Recipients”. Joy PS, Kumar G, Guddati AK, Bhama JK, Cadaret LM. American Journal of Cardiology. 2016 Jan 15; 117(2):240-4.  PMID: 26651456

  18. “Analysis of outcomes of percutaneous coronary intervention in metastatic cancer patients with acute coronary syndrome over a 10-year period”. Guddati AK, Joy PS, Kumar G.  Journal of Cancer Research in Clinical Oncology. 2016 Feb; 142(2):471-9. PMID: 26498773

  19. “Delirium Tremens Leads to Poor Outcomes for Acute Coronary Syndrome.” Joy P.S, Kumar G. Cardiology 2015;132:172-175. PMID: 26277875

  20. "Acute Kidney Injury Requiring Dialysis in Severe Sepsis". Ankit Sakhuja, Gagan Kumar, Shipra Gupta, Tarun Mittal, Amit Taneja, Rahul S Nanchal. American Journal of Respiratory and Critical Care Medicine.  2015 Oct 15;192(8):951-7. PMID: 26120892

  21. “Delirium Tremens is a risk factor for Takotsubo Cardiomyopathy”. Parijat S. Joy, Gagan Kumar. International Journal of Cardiology. 2015 May 1; 191:185-186. PMID 25965629.

  22. “A Non-canonical Pathway from Cochlea to Brain Signals Tissue-Damaging Noise”. Emma N. Flores, Anne Duggan, Thomas Madathany, Ann K. Hogan, Freddie G. Márquez, Gagan Kumar, Rebecca P. Seal, Robert H. Edwards, M. Charles Liberman, Jaime García-Añoveros. Current Biology. 2015 Mar 2; 25(5):606-12. PMID: 25639244.

  23. “Severe Sepsis in Hematopoietic Stem Cell Transplant Recipients”. Kumar G, Ahmad S, Taneja A, Patel J, Guddati AK, Nanchal R.  Critical Care Medicine. 2015 Feb; 43(2):411-21. PMID: 25599465.

  24. "Acute Myocardial Infarction: A National Analysis of the Weekend Effect over Time". Kumar G, Deshmukh A, Sakhuja A, Taneja A, Kumar N, Jacobs E, Nanchal R. Journal of the American College of Cardiology. 2015 Jan 20; 65(2):217-8. PMID: 25593065.

  25.  “Early Trophic Enteral Nutrition Is Associated With Improved Outcomes in Mechanically Ventilated Patients With Septic Shock: A Retrospective Review”. Patel JJ, Kozeniecki M, Biesboer A, Peppard W, Ray AS, Thomas S, Jacobs ER, Nanchal R, Kumar G. Journal of Intensive Care Medicine. 2014 Oct 14. [Epub ahead of print]. PMID: 25315218

  26. “Incidence and Outcomes of Clostridium Difficile-Associated Disease in Hematopoietic Cell Transplant Recipients”. Guddati AK, Kumar G, Ahmed S, Ali M, Kumar N, Hari P, Venu N. International Journal of Hematology. 2014 Jun;99(6):758-65. PMID: 24715522.

  27.  “Tracheobronchial Amyloidosis Managed with Multimodality Therapies." Sommers P, Kumar G, Lipchik R, Patel J. accepted Therapeutic Advances in Respiratory Disease. 2014 Apr;8(2):48-52 2014. PMID: 24594977.

  28. “Non-Traumatic Subarachnoid Hemorrhage in Maintenance Dialysis Hospitalizations: Trends and Outcomes”. Sakhuja A, Schold JD, Kumar G, Katzan I, Navaneethan SD. Stroke. 2014 Jan; 45(1):71-6. PMID: 24253541

  29. “Utilization of mechanical ventilation in asthma exacerbations: A Nationwide analysis.” Nanchal R, Kumar G, Majumdar T, Taneja A, Patel J, Dagar G, Whittle J. Respiratory Care. 2014 May;59(5):644-53. PMID: 24106317

  30. “The Association of Lacking Insurance with Outcomes of Severe Sepsis: Retrospective Analysis of an Administrative Database.” Kumar G, Taneja A, Majumdar T, Jacobs E, Whittle J, Nanchal R. Critical Care Medicine 2014 Mar;42(3):583-91. PMID: 24152590.

  31. “Identifying oncological emergencies”. Guddati AK, Kumar N, Segon A, Joy PS, Marak CP, Kumar G. Medical Oncology 2013 Sep; 30(3):669. PMID: 23873016.

  32. “The Association of Serum Bilirubin Levels on the Outcomes of Severe Sepsis.” Patel JJ, Taneja A, Niccum D, Kumar G, Jacobs E, Nanchal R. Journal of Intensive Care Medicine. 2015 Jan;30(1):23-9. PMID: 23753252.

  33. “Outcomes of Patients Receiving Maintenance Dialysis Admitted Over Weekends.” Sakhuja A, Schold JD, Kumar G, Dall A, Sood P, Navaneethan SD. American Journal of Kidney Diseases 2013 Oct;62(4):763-70. PMID: 23669002.

  34. “Outcomes of morbidly obese patients undergoing invasive mechanical ventilation.” Kumar G, Majumdar T, Taneja A, Dagar G, Deshmukh A, Danesh V, Jacobs E, Nanchal R.  Chest. 2013 Jul 1; 144(1):48-54. PMID: 23349057.

  35. “Pulmonary embolism in patients with CKD and ESRD.” Kumar G, Sakhuja A, Taneja A, Patel J, Majumdar T, Nanchal R.  Clinical Journal of American Society of Nephrology. 2012 Oct;7(10):1584-90. PMID: 22837271.

  36. “Pulmonary Embolism: The Weekend Effect.” Nanchal R, Kumar G, Taneja A , Patel J , Deshmukh A, Tarima S, Whittle J, Jacobs E. Chest. 2012 Sep; 142(3):690-6. PMID: 22459777.

  37. “Clostridium Difficile Infection in Hospitalized Liver Transplant Patients: A Nationwide Analysis”. Ali M, Anathakrishnan A, Ahmad S, Kumar N, Kumar G, Saeian K. Liver Transplantation. 2012 Aug;18(8) 972-8. PMID: 22505356.

  38. “Comparison of Outcomes of Weekend versus Weekend Admissions for Atrial Fibrillation”. Deshmukh A, Kumar G, Pant S, Paydak H. American Journal of Cardiology. 2012 Jul 15; 110(2):208-11. PMID: 22481013.

  39. “Prevalence of Takotsubo Cardiomyopathy in United States”. Deshmukh A, Kumar G, Pant S, Rihal C, Mehta JL. American Heart Journal. 2012 July; 164(1): 66-71. e1. PMID: 22795284.

  40. “Assessing the Credibility of ‘YouTube Approach’ to Health Information on Acute Myocardial Infarction”.  Deshmukh A, Pant S, Murugiah K, Kumar G, Sachdeva R, Mehta JL. Clinical Cardiology, 2012 May; 35(5):281-5. PMID: 22487995.

  41. “Chronic Kidney Disease and End Stage Renal Disease Predict Higher Risk of Mortality in Primary Upper Gastrointestinal Bleed Patients.” Sood P , Kumar G ,Nanchal R , Sakhuja A, Ahmad S. , Ali M. , Kumar N.,  Ross EA. American Journal of Nephrology. 2012 Feb 4;35(3):216-224. PMID: 22310659.

  42. "Nationwide trends of severe sepsis in the twenty first century (2000-2007)". Kumar G, Kumar N, Taneja A, Kaleekal TS, Tarmia S, McGinley E, Jimenez E, Mohan A, Khan RA, Whittle J, Jacobs E, Nanchal R. Chest.  2011 Nov;140(5):1223-31. PMID: 21852297.

  43. "Impact of Joint National Committee VII Report on Hospitalizations for Hypertensive Emergencies in the United States". Deshmukh A, Kumar G, Kumar N, Nanchal R, Gobal F, Mehta JL.  American Journal of Cardiology.  2011 Nov 1; 108(9):1277-82. PMID: 21890093.

  44. "Unbiased counting of neurons in the cochlea of developing gerbils". Richter C.-P., Kumar G, Webster E, Whilton D. Hearing Research. 2011 Aug; 278(1-2): 43-51. PMID: 21329751.

  45. ‘Electrical impedance measurements of cochlear structures using the four-electrode reflection-coefficient technique.’ Kumar G, Chokshi M, and Richter C-P; Hearing Research. 2010;259(1-2): 86-94. PMID: 19857561.

  46. ‘Cellular infilteration accompanying pneumonitis induced by a single moderate dose of X – irradiation in rats’, Szabo S, Ghosh SN, Fish BL, Bodiga S, Tomic R, Kumar G, Morrow N, Moulder JE, Jacobs E, Medhora M. Radiation Research 173, : 4 (April 2010) pp. 545–556. PMID: 20334527.

  47. ‘All Red Is Not Cellulitis – A Case of Lofgren Syndrome’ Kumar G, Kumar N. Wisconsin Medical Journal. 2010; 109(1): 31-33. PMID: 20942298.

  48. ‘Hair cell transducer properties of TRPA1, a channel for pain and hearing’, Nagata K, Duggan A, Kumar G, García-Añoveros J. Journal of Neuroscience. 2005; 25: 4052-4061. PMID: 15843607.

  49. ‘Promontory Test: Its role in Cochlear Implantation’, Kumar G, Deka RC, Jha DN. Indian Journal of Otology. 2002; 8(1): 17 – 20.

  50. ‘Malignant Otitis Externa’, Kumar G, Ganeshan S, Kumar GA. Indian Journal of Clinical Practice. 2002; 13(1): 39 – 44.

  51. ‘Acute Exacerbations of Chronic Bronchitis – Advantages of Cefuroxime Axetil’. Sathia GN, Patra V, Sharma S, Rout S, Kumar G. Indian Journal of Clinical Practice. 2002; 12(11): 27 – 35.

  52. ‘Iron Polymaltose Complex: the safe and effective hematinic’. Kumar G, Ganeshan S. Indian Journal of Clinical Practice Medinews. 2002; April (16 – 30):15.

  53. ‘Asthma in Children – Salbutamol vs. Terbutaline’. Kumar G, Ganeshan S, Khurana Sarabjeet, Tripathy AK. Asian Journal of Paediatric Practice. 2002; 6(1): 17 – 18.

Hair cells.PNG

Side-view hair cells from the semicircular canal demonstrating the presence of the TRPA1 channel on the mechanosensory bundles of stereocilia. The kinocilia, which presumably are not mechanosensory, are labeled in blue (for α-tubulin). TRPA1, labeled in red, is detected in the apical side of the epithelium (a presumed repository or transduction component) and also in the mechanosensory stereocilia(labeled in green for actin). The bottom part of these very long bundles, which contain the tips of numerous shorter stereocilia, labels somewhat more strongly for TRPA1(yellow), which is also detected on the longer stereocilia, as can be more clearly seen in Figure 3n of the manuscript. Thus the localization of TRPA1 is consistent with the occurrence of transduction at the tips of stereocilia. Accordingly, TRPA1 displays channel properties of the hair cell transducer and probably forms its pore. In addition, TRPA1 is present in most nociceptors and is thought to play a parallel role in pain  transduction. 

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